CADTH Lecture Series
CADTH is hosting a series of lectures by prominent scholars and opinion leaders to share their perspective on some of the most pressing issues facing health technology assessment (HTA) and health care today.
Tuesday, February 10, 2015
Judging the Gift from the Box: Reflections on the Power and Significance of Bernie O’Brien’s “Power and Significance”
O’Brien et al.’s 1994 article, “In search of power and significance: Issues in the design and analysis of stochastic cost-effectiveness studies in health care,” introduced researchers to “the feasibility and desirability of constructing statistical tests of economic hypotheses and estimation of cost-effectiveness ratios with associated 95% confidence intervals.” This was an important point in the history of HTA. While economic evaluations were abundant at that time, statistical procedures for assessing uncertainty were virtually non-existent. This presentation will review insights from the challenges of characterizing uncertainty in economic evaluation. The research discussed in Bernie’s seminal 1994 paper is an important foundation upon which modern methods of characterizing uncertainty in economic evaluation are built. This talk marks the anniversary of Bernie’s passing with an appreciation of a remarkable article by a remarkable man.
There is no fee to participate but registration is required.