CCHE Seminar Series – Friday November 7th, 10am – 12pm in HS100

Share Event

As part of the Canadian Centre for Health Economics (CCHE) Friday Health Economics Series, we welcome Dolly Han this Friday November 7th, 10am – 12pm in HS100 (Health Sciences Building 155 College Street). Dolly will explore “Real-World Cost-Effectiveness Analysis Of Second-Line Pemetrexed Versus Docetaxel In The Advanced Non-Small-Cell Lung Cancer Population In Ontario”.

Dolly is a MSc graduate student in the Institute of Health Policy, Management and Evaluation at the University of Toronto, specializing in health technology assessment. She is currently a Submissions Analyst at the pan-Canadian Oncology Drug Review (pCODR). She is also a Student Fellow of the Canadian Centre for Health Economics. She received her undergraduate health sciences degree at the University of Waterloo.


Docetaxel is a common standard treatment for advanced non-small-cell lung cancer in Ontario after first-line platinum-based therapy. In Ontario in 2008, pemetrexed was approved for funding in the second-line setting based on evidence of equal efficacy as docetaxel, with an improved toxicity profile at a higher cost. Net benefit regression was used to determine the cost-effectiveness of pemetrexed compared to docetaxel in the Ontario population using data from health administrative databases. Overall survival was not significantly different in those treated with pemetrexed compared to docetaxel; however, those treated with docetaxel had higher chemotherapy-related toxicities requiring inpatient hospitalization. The incremental net benefit for pemetrexed was -$8611-20,279 for WTP values ranging from $0-150,000/QALY, suggesting that pemetrexed was not cost-effective at the listed drug price. This study illustrated the use of health administrative databases to populate cost and effect outcomes for real-world post-market cost-effectiveness analyses through net benefit regression.

Link to schedule of all CCHE talks:

To be added to the CCHE Health Economics seminar series mailing list please send an e-mail to:

Related Events

Surfacing the Need and Concepts for Alternative Design in Long Term Care


Dec 20, 2023 from 4pm-5:30pm (EST)


IHPME Events

Event Details
Digital fingerprint

Future of Health Leadership, Informatics and Policy (FHLIP) Conference


Feb 22, 2024

University of Toronto – Hart House, Great Hall
Join us at the University of Toronto’s historic Hart House for an insightful exploration of digital health policy and leadership.

IHPME Events

Event Details

Sign up for IHPME Connect.

Keep up to date with IHPME’s News & Research, Events & Program, Recognition, e-newsletter.

* indicates required

Get in Contact


Email Address: ihpme.communications@​

Manages all IHPME-wide communications and marketing initiatives, including events and announcements.