An adapted early warning signs and symptoms (EWSS) intervention to improve early recognition and referral of childhood cancers in Kenya and Cameroon: An Effectiveness Implementation Study. 5 years.
Cancer accounts for a growing proportion of global childhood mortality. There are no known ways to prevent child cancers; early diagnosis and treatment are key to preventing mortality. Interventions to improve early diagnosis and referral of child cancers are effective: they have been linked to increased case detection, earlier stage at diagnosis, and improved overall survival1. However, few such interventions exist in sub-Saharan Africa. Existing effective interventions need to be modified for context, implemented and assessed for effectiveness in sub-Saharan Africa. Our objective is to systematically adapt and implement an established ‘early warning signs and symptoms’ (EWSS) intervention – the St. Siluan campaign developed in South Africa and modified in Ghana – and evaluate its feasibility, implementation barriers and facilitators, cost, and clinical and implementation effectiveness in Cameroon and Kenya. We aim to ultimately decrease mortality from child cancers in Cameroon and Kenya.
2022/27 Principal Applicant. Denburg A (NPI), Gupta S (PI), Barwick M (PI). Co-Investigators: Fowokan A, Githanga J, Macharia W, Martiniuk A. Collaborators: Afungchwi G, Bhutta Z, Freccero P, Hoffman R, Horton S, Karagu A, Mashauri F, Nyangasi M, Orem J, Petricca K, Pondy A, Rogo K, Sonoiya, S. 5 years, CIHR Project Grant, Spring 2022